Glutathione 200 mg/ml – 20 ml

Glutathione 200 mg/ml

Research-grade liquid glutathione solution supplied in a sterile 20 ml glass vial. Glutathione (GSH) is the principal low-molecular-weight intracellular thiol — a tripeptide of glutamate, cysteine and glycine whose free thiol group makes it the central redox buffer of the cell. It is studied in controlled laboratory settings for cellular redox homeostasis, phase II detoxification pathways, enzymatic antioxidant systems and mitochondrial bioenergetics.

Specifications

Research Overview

Glutathione is a tripeptide formed by an atypical γ-peptide bond between the side chain of glutamate and cysteine, followed by a standard bond to glycine. The reactive thiol on the cysteine residue is oxidised to a disulfide when glutathione donates electrons to reactive oxygen species, a reaction catalysed by glutathione peroxidase; the oxidised form is then recycled by glutathione reductase using NADPH. The resulting ratio between the reduced and oxidised forms is widely used in research as a measure of cellular redox state. Glutathione also acts as a cofactor for glutathione S-transferases in the conjugation of electrophilic compounds, and participates in reversible protein S-glutathionylation as part of redox signalling. No therapeutic or clinical claims are made or implied.

Primary Research Areas